Specifically, ChIRP-PCR showed that RBAT1 was enriched in the E2F3 promoter region in three tumor cell lines, whereas a weak RBAT1 enrichment was observed at the E2F3 promoter after RBAT1 suppression (Fig. 6e-g); suggesting that the promoter region of E2F3 was the binding site for lncRNA RBAT1. The gene discussed is E2F3-IT1; the disease is neoplasm.