In particular, ivermectin suppressed MKN1 gastric cancer cell growth in vitro and in vivo (when used at 10 μM and 10 mg/kg respectively) through the inhibition of the nuclear expression of yes-associated protein 1 (YAP1) [50], which plays a key role in gastric carcinogenesis [81]. The gene discussed is YAP1; the disease is gastric cancer.