TGFB1 and neoplasm: The molecular signature of TAMs did not display a specific tumor-supportive polarization nor appear to induce the production of immunosuppressive cytokines Il10 or Tgfβ. Nevertheless, we detected a reduction of markers like iNos, Il1β, and Il12α, important for tumor growth inhibition [43,45], when comparing Ccr2-deficient TAMs to wildtype cells.