This strategy uses intratumoural injection of 30 nm diameter gold nanoparticles modified with polyethylene glycol (PEG) chains with DOTA ligand that complex the therapeutic radionuclide 177Lu and linked to panitumumab that bind the AuNP to epidermal growth factor receptor (EGFR)-positive tumour cells or linked to Trastuzumab that bind to HER2 receptors [53,54]. This evidence concerns the gene EGFR and neoplasm.