Similarly, FPturquoise (cluster B) significantly overlaps with DEGs from models of FTD-ALS (TDP43) (M24, padj = 2.0 × 10−42), CJD (M199, padj = 3.7 × 10−18), and Rett syndrome (M198, padj = 3.1 × 10−3) and more selectively in HD (M81, padj = 1.1 × 10−4) and SCA1 (M151, padj = 5.3 × 10−5) models. Here, TARDBP is linked to Creutzfeldt Jacob disease.