EGFR and lung adenocarcinoma: EGFR mutation rate is 40% to 50% in lung adenocarcinoma (ADC) cases in east Asian populations.6 However, in Asian SqCC patients, incidence of EGFR mutation is relatively low, varying from 2% to 13%.7, 8, 9, 10 The role of EGFR mutation status testing and EGFR‐TKIs in SqCC remains controversial.