NRN1 and diabetic neuropathy: It is probably explained that diabetic neuropathy is a chronic complication1, 4, 5, 6; therefore, SCs may lose their survivability as a result of the cumulative effect of long standing hyperglycaemia marked by elevated HbA1c, and exogenous neuritin, if given for a certain period and as a single treatment, needs to be dosed up to certain extent to revive the poorly viable diabetic SCs with early apoptosis and promote cell proliferation as shown in our experiment.