POMC and infantile spasms: We therefore strongly encourage all clinicians who carefor children with infantile spasms to use standard first-line treatment(ACTH, prednisolone, or vigabatrin). Although there may beconcerns regarding the use of high-dose oral steroid or ACTH in childrenwith potential COVID-19 exposure, vigabatrin should be considered in suchcases as opposed to nonstandard therapies or delaying treatment.