Additionally, some of these cytokines were increased in the first 36 h after infusion of CAR T cells, including IFN-γ, IL-6, IL-8, IL-10, IL-15, MCP-1, TNFRp55, and MIP-1β, and demonstrated similar kinetic patterns in B-ALL, CLL, and NHL patients, suggesting that these cytokines may be used to predict severe CRS (grade ≥ 4) [2, 32]. The gene discussed is CXCL8; the disease is congenital rubella syndrome.