CD79A and common variable immunodeficiency: In addition, these mice develop abnormal spleens and lymph nodes with a decreased number of B- and T-cells in the germinal centers and parafollicular region, respectively, leading to decreased IgA and IgG levels in the serum, which, combined with gut dysbiosis, may be a cause for gluten-sensitive enteropathies in ‘common variable immunodeficiency’ (CVID) [74–76].