Circ-ASAP1 was reported to facilitate HCC cell proliferating and invading processes by regulating miR-326/miR-532-5p-MAPK1 signaling and mediate tumor-related-macrophage infiltrating process through the control over the miR-326/miR-532-5p-CSF-1 path. The gene discussed is CSF1; the disease is neoplasm.