In patients having COVID-19, the levels of chemokines and cytokines are noted abnormal which includes vascular epithelial growth factor (VEGF), hepatocyte growth factor (HGF), TNF-α, MIP 1-α, MCP-1, IP-10, IFN-γ, GM-CSF, G-CSF, M-CSF, IL-17, IL-13, IL-12, IL-10, IL-7, IL-6, IL-1, IL-2 and IL-4 [40]. This evidence concerns the gene IL4 and COVID-19.