CDH1 and cancer: Many studies and researches have reported that for most cancers, as the cancer progresses, Vimentin has increased (Niknami et al., 2017[12]; Xiao et al., 2015[22]), while E-cadherin has decreased (Bruun et al., 2014[3]; Kolijn et al., 2015[8]; Xiao et al., 2015[22]; Ye et al., 2015[23]).