Among the distinct parameters analyzed, cancer cell characteristics, including CDH1 protein levels and ROR risk, either remained significant but with low pertinence (CDH1: HR 1.23; CI95% [1.007–1.51] p = 0.042) or even lost significance (ROR risk) in multivariate analyses (Table 2), indicating that they are not the most significant indicators of relapse in luminal BC patients. The gene discussed is CDH1; the disease is breast cancer.