SARS-CoV-2 infection alters gene expression, including tissue inhibitor of metalloproteinase (TIMP)3, angiotensinogen (AGT), TGFB1, connective tissue growth factor (CTGF), vascular endothelial growth factor (VEGF) A and FN1, and these changes are also observed in lung tissues from patients with lung fibrosis. This evidence concerns the gene TGFB1 and pulmonary fibrosis.