DKK1 and gastric cancer: The authors found that miR-501-5p may directly bind and suppress several important repressors of the Wnt/beta-catenin signaling cascade [such as GSK3 beta, dickkopf-related protein 1 (DKK1) and naked cuticle 1 (NKD1)], which lead to hyperactivated signaling in gastric cancer cells [54].