These results do not exclude the possibility that the MIA-evoked disturbances of the CX3CL1–CX3CR1 system in the non-responsive offspring, observed in our study, potentiate the susceptibility to induction of the behavioural deficits, consistent with the “two-hit” hypothesis of schizophrenia [116]. The gene discussed is CX3CR1; the disease is schizophrenia.