Because Ndst3-deficient mice have been reported to show subtle changes in anxiety-like behavior [21], and because Ndst3 mutations have been linked to shizophrenia and bipolar disorder in humans [22] that both include anxiety as a symptom, we next assessed anxiety, anxiety-related behavior and exploratory behavior in Ndst1f/f;L7-Cre+ mice and Ndst1+/+;L7-Cre+ control mice. Here, NDST1 is linked to bipolar disorder.