SRC and Miyoshi myopathy: In particular, CD26 was found to induce the nuclear translocation of the transcription factor TWIST1 via SRC activation (Figure 2); this resulted in enhanced expression and secretion of periostin [46], a matricellular protein involved in the promotion of cell migration and invasion [97], the low expression of which has been suggested as a prognostic factor for longer overall survival of MM patients [98].