This vaccine contains a portion of the Pf circumsporozoite protein (CSP) along with hepatitis B virus envelope protein and chemical adjuvant, targeting the sporozoite (a stage of the malaria parasite released by infected mosquitoes) or liver-stage parasites (sporozoites infect hepatocytes and develop daughter cells for the subsequent blood-stage of infection) [13]. The gene discussed is DNAJC5; the disease is malaria.