NUP98 and acute myeloid leukemia: The fusion of NUP98 with the homeobox protein Hox-A9 (HOXA9), NUP98-HOXA9, that results from t(7;11)(p15;p15), has been studied as the prototype for the oncogenic mechanisms governing the actions of NUP98 fusions with homeodomain (HD) proteins in AML [9].