The mesothelioma samples used for testing OCT4, NANOG and SOX2 expression were also used for investigating the expression of phosphorylated (activated) PI3K (Tyr607; p-PI3K), phosphorylated/activated AKT (Ser473; p-AKT) and BCL2 (Figure 2). The gene discussed is PIK3CA; the disease is mesothelioma.