The numbers of IFN-γ+TNF-α+IL-2+ T cells were the highest among the multifunctional T cells in the Rv2882c-Rv2005c immunized mice at 12 weeks post infection (Figure 6B), and the numbers of IFN-γ+TNF-α+ T cells were sustained until 20 weeks postinfection. The gene discussed is TNF; the disease is infection.