Fibrils can vary in size, usually ranging between 16 to 24 nm, which is larger than those described in amyloidosis (4–11 nm).[2] Under immunofluorescence, it can stain positive for Immunoglobulin G (IgG), complement component 3 (C3), Kappa And Lambda light chains.[3] Certain IgG subclasses, such as IgG4, are seen more often than others.[2] In general, FGN has a poor prognosis despite therapeutic interventions. The gene discussed is C3; the disease is amyloidosis.