NFKB1 and autoimmune disease: P. lactiflora is a Chinese folk medicine that have been used to treat a number illnesses, including pain, inflammation, and autoimmune diseases for over a millennia.[8] The root of P. lactiflora contains several bioactive compounds, such as paeoniflorin, albiflorin, penta-O-galloyl-β-d-glucose with anti-inflammatory and other health functions.[9] A recent study reported that paeoniflorin, obtained from P. lactiflora can mitigate inflammatory pain by suppressing Akt-NF-kB pathway.[10]C.