Dysferlinopathies (LGMD type 2B and Miyoshi myopathy) include autosomal-recessive muscle diseases caused by pathogenic variants in the dysferlin gene (DYSF), characterized by a selective and progressive involvement of the proximal and/or distal muscles of the limb girdles.[7] The age at onset of muscle weakness varies widely, but usually occurs in the teenage years or early adulthood. This evidence concerns the gene DYSF and Miyoshi myopathy.