Expression scores of hemopexin in cases with lymph node metastasis were 0 in 21, 1 in 37, 2 in 54 and 3 in 16 cases (N1; 0 in 18, 1 in 28, 2 in 36 and 3 in 8 cases, N2; 0 in 2, 1 in 10, 2 in 18 and 3 in 8 cases). This evidence concerns the gene HPX and metastatic malignant neoplasm in the lymph nodes.