Clinical studies have shown that BM can achieve anti-inflammatory and anti-oxidant effects by activating nuclear factor erythroid 2-related factor 2 (Nrf2) and inhibiting nuclear factor-κB (NF-κB) [74] by effectively improving glomerular filtration rate in patients with chronic kidney disease (CKD) [75]. The gene discussed is NFKB1; the disease is chronic kidney disease.