Spolnicka et al. [11] tested an epigenetic model composed of five markers from five genes (ELOVL2, C1orf132, KLF14, FHL2 and TRIM59) for the estimation of chronological age in three disease groups (late and early onset Alzheimer’s disease, Graves’ disease). The gene discussed is KLF14; the disease is early-onset autosomal dominant Alzheimer disease.