Our targeted analysis on the genetic data from the MTA cohort found significant associations between ADHD (persistent phenotype) and variants rs4668077 (P = 6.47 × 10−6; PFDR = 4.43 × 10−4; Table 2a) and rs139609178 (P = 1.01 × 10−4; PFDR = 4.65 × 10−3; Table 2b) in the genes encoding for CERS6 and CERS2, respectively. Here, CERS2 is linked to attention deficit-hyperactivity disorder.