There was a significant increase in tumor volume and weight (Fig. 3b, c), elevated Bcl-2 and VEGF expression, declined Bax and cleaved caspase3 expression (Fig. 3d, e), as well as increased CD31 expression (Fig. 3f) in miR-130b-3p agomir-injected nude mice. The gene discussed is PECAM1; the disease is neoplasm.