CXCL8 and Huntington disease: In chcGAS KO and chSTING KO cells, the IFNβ, OASL, IL-1β, and IL-8 transcript productions were significantly (p < 0.05) reduced relative to control HD cells, whereas the viral C11R gene expressions were increased significantly (p < 0.05) relative to control HD11 cells (Figure 6A and Figure S3).