A study based on finding provide a novel insight into the mechanism by which EGCG, affecting multiple ET(A)R-dependent pathways, may inhibit ovarian carcinoma growth, proposing that EGCG may be beneficial in inhibiting as well as treating ovarian carcinoma in which ET(A)R activation by ET-1 plays a valuable role in tumor growth as well as progression [55]. The gene discussed is EDN1; the disease is ovarian carcinoma.