IL27 and viral infectious disease: Moreover, considering that the correct regulation of both the induction and subsequent control of inflammation during respiratory infections is imperative in minimizing severe immunopathology, the detailed study of the influence of NV1505 and PG1505 on the kinetics of IFN-β, IFN-γ, IL-6, and IL-27 productions in the respiratory tract after primary viral infections and secondary pneumococcal pneumonia would be of great value to gain a better understanding of the mechanisms involved in their beneficial effects.