In a sporadic context, one study reported the presence of TERTp mutations in 2% of the FTA and 17% of atypical FTA and another study reported one case of FTA with TERT, HRAS, and EIF1AX mutations [28] which lead the authors to conclude that this could be an early event in thyroid tumours that still had not developed malignant features [29]. This evidence concerns the gene EIF1AX and thyroid tumor.