PLCD1 and inflammatory bowel disease: Besides the upregulated molecules, some lncRNAs were found to be downregulated in IBD biopsies, such as cyclin-dependent kinase inhibitor 2B AS1 (CDKN2B-AS1) [95], BC043570, HOXD-AS1, and phospholipase C delta 1 (PLCD1) [93].