LCN2 and encephalitis: Subgroup analyses showed that adding LCN2 to the diagnostic model consisting of leukocytes, protein, lactate and glucose improved the AUROC for differentiation between BM and TBM from 0.89 to 0.93, but slightly improved the discrimination between BM from other infections such as encephalitis and patients with other CNS infections (Fig. 4(D) and Fig. S4).