PRKCH and breast carcinoma: As shown in Fig 1A, the frequency of PKCλ gene amplification was lower in both breast cancer datasets tested (2.1% or 4.6% in TCGA, 3.5% in METABRIC) than in the lung (18.0% or 33.1% in TCGA) or ovarian (19.2% or 31.4% in TCGA) cancer datasets.