GCA and hydrops fetalis: As compared to the condition when all HF-remodelled factors were considered, absence of Jup(max) or GCa remodelling produced a larger increase in APD90, CaT amplitude and SR Ca2+ content; absence of Jrel(max) remodelling produced a smaller increase in SR Ca2+ content, and absence of Gto remodelling produced a smaller increase in APD90 relative to control.