For the meta-analysis of the association between HIF1A Pro582Ser polymorphism and the risk of diabetes, no evidence of significant publication bias was detected by the Begg’s test (P = 0.089 for allelic genetic model; P = 0.602 for homozygous genetic model; P = 0.734 for dominant genetic model; P = 0.296 for recessive genetic model). The gene discussed is HIF1A; the disease is diabetes mellitus.