A series of factors, including patient age, gender, body mass index (BMI), T classification, N classification, EBV DNA copy number, LDH concentration, hs‐CRP concentration, VCA‐IgA titer, EA‐IgA titer, progression status, and INSL5 concentration, were assessed in the univariate Cox regression analysis to test their association with the OS and DFS of NPC patients. This evidence concerns the gene CRP and nasopharyngeal carcinoma.