In the final multivariable logistic regression model, we found that increased NEU (OR: 58.35; 95%CI: 2.16‐1571.69; P = .0155), hs‐CRP (OR: 14.90; 95%CI: 1.27‐171.10; P = .0300), CK (OR: 161.62; 95%CI: 6.45‐4045.20; P = .0020), and BUN (OR: 11.18; 95%CI: 1.36‐91.62; P = .0244) were independent risk factor of COVID‐19 in‐hospital death. Here, CRP is linked to COVID-19.