In othes studies are described the association between the degree of the methylation of the promoters of the gene NR3C1, with the presence of normotension, hypotension, and hypertension in a group of pregnant women, and how these can be found present independently from confounding variables such as tobacco use, family history of High Blood Pressure (HBP), or body mass index (BMI) (12, 13). This evidence concerns the gene NR3C1 and hypertensive disorder.