ULBP1 and hepatocellular carcinoma: The observation that serum ULBP1 falls in patients with active HBV following one year of HBV treatment with the nucleotide reverse-transcriptase inhibitor tenofovir, coupled with the numerically greater (but not statistically significant) ULBP1 in HBV-associated HCC than in HCC without HBV or HCV suggests a direct effect of HBV on ULBP1 production.