LPAR1 was significantly lowly expressed in PRAD, breast invasive carcinoma (BRCA), bladder urothelial carcinoma (BLCA), colon adenocarcinoma (COAD), rectum adenocarcinoma (READ), head and neck cancer (HNSC), esophageal carcinoma (ESCA), kidney renal clear cell carcinoma (KIRC), kidney chromophobe (KICH), liver hepatocellular carcinoma (LIHC), thyroid carcinoma (THCA), stomach adenocarcinoma (STAD), and uterine corpus endometrial carcinoma (UCEC). The gene discussed is LPAR1; the disease is rectum adenocarcinoma.