CD163 and diabetes mellitus: In this study, when we correlated the protein and gene expression of CD163 with the demographic variables and periodontal parameters in both groups, we found that though in CP (Group I), CD163 levels did not show a positive correlation with demographic and periodontal parameters (Table 2), however, in the CP+DM (Group II), it showed a significant positive correlation with PI (p-value 0.001), BOP (p-value 0.001), PPD (p-value 0.001), and CAL (p-value 0.001) (Table 3).