IGFBP2 and cancer: Compared with PNT2 cells, the association was decreased by 82% (p < 0.01) in DU145 cells and by 76% (p = 0.05) in LNCaP cells (Figure 4E), indicating a strong interaction between FOXA1 and the IGFBP-2 gene in normal prostate cells and a markedly reduced interaction between the two in cancer cells