IGFBP2 and prostate cancer: Correlation analysis between IGFBP-2 and clinicopathological parameters of prostate cancer showed that IGFBP-2 was not significantly associated with age (p = 0.834), pre-operative PSA level (p = 0.051), Gleason score (p = 0.192), pathologic stage (p = 0.813) or lymph node involvement (p = 0.850) in the Southmead cohort (Table 1).