ACHE and Alzheimer disease: Amla (Emblica officinalis), the Indian gooseberry, has been shown to exert diverse neuroprotective pharmacodynamic actions [28]; to have potent radical scavenging effects [29]; to have a high degree of neuroprotective potential in a panel of bioassays that targeted protein glycation, carbonyl stress, acetylcholinesterase inhibition, oxidative stress, Aβ fibrillation, and neuroinflammation [30]; and to improve the acetylcholinesterase activity, brain antioxidant enzymes, and cognitive functions in a rat model of AD [31].