In the liver tissue, compared with HF group rats, AM group rats significantly enhanced the mRNA expression of peroxisome proliferator-activated receptor α (PPARα), peroxisome proliferator-activated receptor γ (PPARγ), small heterodimer partner (SHP), G protein-coupled bile acid receptor (TGR5), fibroblast growth factor 15 (FGF15), fibroblast growth factor 4 (Fgfr4), bile salt export protein (BSEP) and downregulated the mRNA expression of cholesterol-7a-hydroxylase (CYP7A1) (Fig. 3c). This evidence concerns the gene FGFR4 and hydrops fetalis.