Moreover, several target genes listed in Table 2 (GRB2, HNF4A, IL2RB, INSR, KMT2A, NR2E1 and STAT1) were also identified in transcriptomic analysis of cord blood of maternal obesity [38], which agrees with the current study. The gene discussed is INSR; the disease is obesity due to melanocortin 4 receptor deficiency.